Guidelines for the first line management of classical Hodgkin lymphoma.
نویسندگان
چکیده
Follows, George A; Ardeshna, Kirit M; Barrington, Sally F; Culligan, Dominic J; Hoskin, Peter J; Linch, David; Sadullah, Shalal; Williams, Michael V; Wimperis, Jennifer Z; The British Committee for Standards in Haematology. In: British Journal of Haematology, Vol. 166, No. 1, 07.2014, p. 34-49. Úvod: Hodgkinův lymfom je charakterizován přítomností Hodgkinových a Reed-Sternbergových (HRS) buněk v buněčném infiltrátu z nenádorových zánětlivých buněk , které tvoří většinu tumorózní tkáně. HRS buňky jsou klonální B-lymfocyty, které postrádají typické B-buněčné povrchové antigeny. Klasický Hodgkinův lymfom se obvykle projeví nebolestivou lymfadenopatií v horní polovině těla, systémové B-příznaky jsou přítomné asi ve 25% případů.
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ورودعنوان ژورنال:
- British journal of haematology
دوره 166 1 شماره
صفحات -
تاریخ انتشار 2014